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On April 1, 2026, the FDA approved orforglirpon under the brand name Foundayo to reduce excess body weight and maintain weight reduction long term in: Adults with obesity Adults with overweight and at least one weight-related medical condition Like other GLP-1s for weight loss, orforglipron is also indicated in combination with a reduced-calorie diet and increased physical activity

CarelonRx is Anthems in-house PBM and tends to have stricter step therapy for newer GLP-1s

A poorly balanced plate can leave you undernourished even if weight loss continues

Anti-nausea medications are prescribed separately through your doctor and are not included in PlexusDx pricing

Rare but important considerations include pancreatitis and gallbladder disease